The UMD-MSH2 mutations database
Record ID: 1704

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.65T>Gp.Phe22Cys

wt codonwt aamutant codonmutant aamutational eventmutation type
TTCPheTGCCysT->GTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Mismatch binding Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0.880.00 (pathogenous)82 (Pathogenous)

Patient and sample data


Sample IDPatient status
7_4517 (N0470)2680E040940Relative

Clinical data


Symptom

Reference


Reference IDReference
7Unpublished data