The UMD-MSH2 mutations database
Record ID: 1074

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.2075G>Tp.Gly692Val

wt codonwt aamutant codonmutant aamutational eventmutation type
GGGGlyGTGValG->TTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
ATPase Yes, non coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
10.00 (pathogenous)82 (Pathogenous)

Patient and sample data


Sample IDPatient status
33_PSL 375__06-033Relative

Clinical data


Symptom

Reference


Reference IDReference
33Unpublished data