The UMD-MSH2 mutations database
Record ID: 1044

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.IVS4+1del (c.792+1del)

wt codonwt aamutant codonmutant aamutational eventmutation type
CAGGlnspl+1Spl.del

StructureKey Residue (HCD)Pyrimidin doubletCpG
EXO1 stabilization 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Impact on splicing
Splice site type Wild type sequence CV Mutant type sequence CV Variation (%)
Donor
CAGgtacat
79 _
CAGgtacat
79 _
0 %

Patient and sample data


Sample IDPatient status
31_H710_H710-1_H710-1ARelative

Clinical data


Symptom

Reference


Reference IDReference
31Unpublished data