The UMD-MSH2 mutations database
Statistics: Sequence of exon 12

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Potential stop codons from exon 12

AA position	Wild type codon	Wild type AA	exon	Species
588	TAT	Tyr	12	1
589	GTA	Val	12	1
590	GAA	Glu	12	1
591	CCA	Pro	12	1
592	ATG	Met	12	1
593	CAG	Gln	12	1
594	ACA	Thr	12	1
595	CTC	Leu	12	1
596	AAT	Asn	12	1
597	GAT	Asp	12	1
598	GTG	Val	12	1
599	TTA	Leu	12	1
600	GCT	Ala	12	1
601	CAG	Gln	12	1
602	CTA	Leu	12	1
603	GAT	Asp	12	1
604	GCT	Ala	12	1
605	GTT	Val	12	1
606	GTC	Val	12	1
607	AGC	Ser	12	1
608	TTT	Phe	12	1
609	GCT	Ala	12	1
610	CAC	His	12	1
611	GTG	Val	12	1
612	TCA	Ser	12	1
613	AAT	Asn	12	1
614	GGA	Gly	12	1
615	GCA	Ala	12	1
616	CCT	Pro	12	1
617	GTT	Val	12	1
618	CCA	Pro	12	1
619	TAT	Tyr	12	1
620	GTA	Val	12	1
621	CGA	Arg	12	1
622	CCA	Pro	12	1
623	GCC	Ala	12	1
624	ATT	Ile	12	1
625	TTG	Leu	12	1
626	GAG	Glu	12	1
627	AAA	Lys	12	1
628	GGA	Gly	12	1
629	CAA	Gln	12	1
630	GGA	Gly	12	1
631	AGA	Arg	12	1
632	ATT	Ile	12	1
633	ATA	Ile	12	1
634	TTA	Leu	12	1
635	AAA	Lys	12	1
636	GCA	Ala	12	1
637	TCC	Ser	12	1
638	AGG	Arg	12	1
639	CAT	His	12	1
640	GCT	Ala	12	1
641	TGT	Cys	12	1
642	GTT	Val	12	1
643	GAA	Glu	12	1
644	GTT	Val	12	1
645	CAA	Gln	12	1
646	GAT	Asp	12	1
647	GAA	Glu	12	1
648	ATT	Ile	12	1
649	GCA	Ala	12	1
650	TTT	Phe	12	1
651	ATT	Ile	12	1
652	CCT	Pro	12	1
653	AAT	Asn	12	1
654	GAC	Asp	12	1
655	GTA	Val	12	1
656	TAC	Tyr	12	1
657	TTT	Phe	12	1
658	GAA	Glu	12	1
659	AAA	Lys	12	1
660	GAT	Asp	12	1
661	AAA	Lys	12	1
662	CAG	Gln	12	1
663	ATG	Met	12	1
664	TTC	Phe	12	1
665	CAC	His	12	1
666	ATC	Ile	12	1
667	ATT	Ile	12	1
668	ACT	Thr	12	1
669	GGC	Gly	12-13	1

Red: Amino acids that can be mutated in a stop codon by a single substitution (example: GAT -> TAG)
Species: 1=Human; 2=Mammals; 3=Vertebrates