The UMD-MSH2 mutations database
Statistics: Sequence of exon 11



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Potential stop codons from exon 11

AA position Wild type codon Wild type AA exon Species
555
AAA
Lys
11
1
556
TTG
Leu
11
1
557
ACT
Thr
11
1
558
TCT
Ser
11
1
559
TTA
Leu
11
1
560
AAT
Asn
11
1
561
GAA
Glu
11
1
562
GAG
Glu
11
1
563
TAT
Tyr
11
1
564
ACC
Thr
11
1
565
AAA
Lys
11
1
566
AAT
Asn
11
1
567
AAA
Lys
11
1
568
ACA
Thr
11
1
569
GAA
Glu
11
1
570
TAT
Tyr
11
1
571
GAA
Glu
11
1
572
GAA
Glu
11
1
573
GCC
Ala
11
1
574
CAG
Gln
11
1
575
GAT
Asp
11
1
576
GCC
Ala
11
1
577
ATT
Ile
11
1
578
GTT
Val
11
1
579
AAA
Lys
11
1
580
GAA
Glu
11
1
581
ATT
Ile
11
1
582
GTC
Val
11
1
583
AAT
Asn
11
1
584
ATT
Ile
11
1
585
TCT
Ser
11
1
586
TCA
Ser
11
1
587
GGC
Gly
11-12
1

Red: Amino acids that can be mutated in a stop codon by a single substitution (example: GAT -> TAG)
Species: 1=Human; 2=Mammals; 3=Vertebrates