The UMD-MSH2 mutations database
Statistics: Sequence of exon 10

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Potential stop codons from exon 10

AA position	Wild type codon	Wild type AA	exon	Species
505	TTG	Leu	10	1
506	GAC	Asp	10	1
507	CCT	Pro	10	1
508	GGC	Gly	10	1
509	AAA	Lys	10	1
510	CAG	Gln	10	1
511	ATT	Ile	10	1
512	AAA	Lys	10	1
513	CTG	Leu	10	1
514	GAT	Asp	10	1
515	TCC	Ser	10	1
516	AGT	Ser	10	1
517	GCA	Ala	10	1
518	CAG	Gln	10	1
519	TTT	Phe	10	1
520	GGA	Gly	10	1
521	TAT	Tyr	10	1
522	TAC	Tyr	10	1
523	TTT	Phe	10	1
524	CGT	Arg	10	1
525	GTA	Val	10	1
526	ACC	Thr	10	1
527	TGT	Cys	10	1
528	AAG	Lys	10	1
529	GAA	Glu	10	1
530	GAA	Glu	10	1
531	AAA	Lys	10	1
532	GTC	Val	10	1
533	CTT	Leu	10	1
534	CGT	Arg	10	1
535	AAC	Asn	10	1
536	AAT	Asn	10	1
537	AAA	Lys	10	1
538	AAC	Asn	10	1
539	TTT	Phe	10	1
540	AGT	Ser	10	1
541	ACT	Thr	10	1
542	GTA	Val	10	1
543	GAT	Asp	10	1
544	ATC	Ile	10	1
545	CAG	Gln	10	1
546	AAG	Lys	10	1
547	AAT	Asn	10	1
548	GGT	Gly	10	1
549	GTT	Val	10	1
550	AAA	Lys	10	1
551	TTT	Phe	10	1
552	ACC	Thr	10	1
553	AAC	Asn	10	1
554	AGC	Ser	10-11	1

Red: Amino acids that can be mutated in a stop codon by a single substitution (example: GAT -> TAG)
Species: 1=Human; 2=Mammals; 3=Vertebrates