The UMD-MSH2 mutations database
Statistics: Sequence of exon 1

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Potential stop codons from exon 1

AA position	Wild type codon	Wild type AA	exon	Species
1	ATG	Met	1	1
2	GCG	Ala	1	1
3	GTG	Val	1	1
4	CAG	Gln	1	1
5	CCG	Pro	1	1
6	AAG	Lys	1	1
7	GAG	Glu	1	1
8	ACG	Thr	1	1
9	CTG	Leu	1	1
10	CAG	Gln	1	1
11	TTG	Leu	1	1
12	GAG	Glu	1	1
13	AGC	Ser	1	1
14	GCG	Ala	1	1
15	GCC	Ala	1	1
16	GAG	Glu	1	1
17	GTC	Val	1	1
18	GGC	Gly	1	1
19	TTC	Phe	1	1
20	GTG	Val	1	1
21	CGC	Arg	1	1
22	TTC	Phe	1	1
23	TTT	Phe	1	1
24	CAG	Gln	1	1
25	GGC	Gly	1	1
26	ATG	Met	1	1
27	CCG	Pro	1	1
28	GAG	Glu	1	1
29	AAG	Lys	1	1
30	CCG	Pro	1	1
31	ACC	Thr	1	1
32	ACC	Thr	1	1
33	ACA	Thr	1	1
34	GTG	Val	1	1
35	CGC	Arg	1	1
36	CTT	Leu	1	1
37	TTC	Phe	1	1
38	GAC	Asp	1	1
39	CGG	Arg	1	1
40	GGC	Gly	1	1
41	GAC	Asp	1	1
42	TTC	Phe	1	1
43	TAT	Tyr	1	1
44	ACG	Thr	1	1
45	GCG	Ala	1	1
46	CAC	His	1	1
47	GGC	Gly	1	1
48	GAG	Glu	1	1
49	GAC	Asp	1	1
50	GCG	Ala	1	1
51	CTG	Leu	1	1
52	CTG	Leu	1	1
53	GCC	Ala	1	1
54	GCC	Ala	1	1
55	CGG	Arg	1	1
56	GAG	Glu	1	1
57	GTG	Val	1	1
58	TTC	Phe	1	1
59	AAG	Lys	1	1
60	ACC	Thr	1	1
61	CAG	Gln	1	1
62	GGG	Gly	1	1
63	GTG	Val	1	1
64	ATC	Ile	1	1
65	AAG	Lys	1	1
66	TAC	Tyr	1	1
67	ATG	Met	1	1
68	GGG	Gly	1	1
69	CCG	Pro	1	1
70	GCA	Ala	1	1
71	GGA	Gly	1-2	1

Red: Amino acids that can be mutated in a stop codon by a single substitution (example: GAT -> TAG)
Species: 1=Human; 2=Mammals; 3=Vertebrates