The UMD-MSH2 mutations database
Val to Deletion mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Val63X	c.187delG	1	63	Mismatch binding		Small rearrangement	Fr.	Stop at 63	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 185 4_Gr2007-28_24705_3090 - 4
p.Val147CysfsX4	c.439_440delGT	3	147	Connector		Small rearrangement	Fr.	Stop at 150	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3170 4_Ni1401347995261 - 4
p.Val150AlafsX3	c.449_522del	3	150	Connector		Small rearrangement	Fr.	Stop at 152	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3239 19_1908919089-00119089-001 - 19
p.Val437X	c.1309delG	8	437	EXO1 stabilization		Small rearrangement	Fr.	Stop at 437	3
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 492 17_Paris-F9880_5001117_90 - 17 2135 7_-6186---E060221 - 7 2137 7_-61865037E060221 - 7
p.Val463IlefsX8	c.1387_1400del	9	463	EXO1 stabilization		Small rearrangement	Fr.	Stop at 470	5
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 171 4_T04095_18202_1223 - 4 687 19_11376_11376-001_11376- - 19 688 19_11376_11376-002_11376- - 19 689 19_11376_11376-006_11376- - 19 690 19_11376_11376-008_11376- - 19
p.Ser703_Val712del	c.2106_2135del	13	702	ATPase		Small rearrangement	InF	In frame del	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 71 2_PLP-HEGP EXT57_15605_15 - 2 1397 41_HNPCC109_HNPCC109001_- - 41
p.Ser723HisfsX3	c.2166_2173del	13	722	ATPase		Small rearrangement	Fr.	Stop at 725	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 202 4_CF1275_---_--- - 4