The UMD-MSH2 mutations database
Ser to Stop mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Ser142X	c.425C>A	3	142	Connector		Small rearrangement	Tv	C->A	3
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 809 19_4768_4768-001_4768-001 - 19 810 19_4768_4768-002_4768-002 - 19 811 19_4768_4768-003_4768-003 - 19
p.Ser281X	c.842C>G	5	281	EXO1 stabilization		Small rearrangement	Tv	C->G	11
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 467 8_F175_B041277_04-0831 - 8 468 8_F175_B061120_06-0863 - 8 469 8_F175_B031772_G1 - SF19 - 8 470 8_F175_B031771_G1 - SF20 - 8 471 8_F175_B031871_G1 - SF21 - 8 472 8_F175_B032759_G2 - 148 - 8 871 19_15153_15153-001_15153- - 19 1332 37_L08.023-E_6407_60842 - 37 1333 37_L08.023-E_6408_60844 - 37 1334 37_L08.023-E_7611_70935 - 37 1335 37_L08.023-E_7612_70936 - 37
p.Ser473X	c.1418C>G	9	473	EXO1 stabilization		Small rearrangement	Tv	C->G	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 359 6_611261_B00069807_S 2809 - 6
p.Ser494X	c.1481C>A	9	494	EXO1 stabilization		Small rearrangement	Tv	C->A	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 172 4_CRH06114_22238_--- - 4
p.Ser612X	c.1835C>G	12	612	Lever		Small rearrangement	Tv	C->G	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 1222 37_L10.067_11968_101745 - 37 2947 19_L10.06711968109757 - 19
p.Ser743X	c.2228C>A	14	743	ATPase		Small rearrangement	Tv	C->A	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 203 4_C02030 _17116_703 - 4
p.Ser743X	c.2228C>G	14	743	ATPase		Small rearrangement	Tv	C->G	6
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 2956 19_L07.4911340117041 - 19 1272 37_F07.105_6301_60151 - 37 1273 37_F07.105_7424_70003 - 37 1274 37_F07.105_9747_83192 - 37 1275 37_F07.105_11420_93539 - 37 2865 37_L07.4925097150519 - 37