The UMD-MSH2 mutations database
Ser to Deletion mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Ser77CysfsX4	c.229_230delAG	2	77	Mismatch binding		Small rearrangement	Fr.	Stop at 80	7
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 1278 37_L04.01_2061_20826 - 37 1279 37_L04.01_2060_20880 - 37 1280 37_L04.01_2062_21085 - 37 1281 37_L04.01_2535_27674 - 37 1282 37_L04.01_20692_133170 - 37 1283 37_L04.01_20692_134180 - 37 2866 37_L04.0121106134890/135296 - 37
p.Ser87CysfsX11	c.260_264delCTTTT	2	87	Mismatch binding		Small rearrangement	Fr.	Stop at 97	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 786 19_6918_6918-001_6918-001 - 19 787 19_6918_6918-008_6918-008 - 19
p.Gln130ValfsX2	c.387_388delTC	3	129	Connector		Small rearrangement	Fr.	Stop at 131	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 216 4_CF956_---_--- - 4 1029 31_H211_H211_1_H211_1_A - 31
p.Ser268TyrfsX6	c.803delC	5	268	EXO1 stabilization		Small rearrangement	Fr.	Stop at 273	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 1648 7_4353 (04K223)2478E04060 - 7
p.Ser271ArgfsX2	c.811_814delTCTG	5	271	EXO1 stabilization		Small rearrangement	Fr.	Stop at 272	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 1084 33_TNN 247__03-1124 - 33 2552 SO_-3983---G05779 - 71
p.Ser271CysfsX12	c.812_813delCT	5	271	EXO1 stabilization		Small rearrangement	Fr.	Stop at 282	6
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 466 8_44989_80751_08-417121EG - 8 869 19_12604_12604-001_12604- - 19 870 19_12604_12604-005_12604- - 19 3047 8_449896346108-117131EGS - 8 3180 19_2801128011-00128011-001 - 19 3181 19_1948719487-00219487-002 - 19
p.Ser479X	c.1435_1436delAG	9	479	EXO1 stabilization		Small rearrangement	Fr.	Stop at 479	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 2645 SO_-4822---G07233 - 71
p.Ser558PhefsX2	c.1673delC	11	558	EXO1 stabilization		Small rearrangement	Fr.	Stop at 559	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 2331 SO_-1315---G00330 - 71
p.Ser585GlnfsX4	c.1753_1756delTCTT	11	585	Lever		Small rearrangement	Fr.	Stop at 588	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3207 2_02-OCN1331642498215047440 - 2
p.Ser860TyrfsX17	c.2579_2592del	15	860	Helix-turn-helix		Small rearrangement	Fr.	Stop at 876	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 2253 7_1313014583E111688 - 7 2259 7_1313015655E120559 - 7