The UMD-MSH2 mutations database
Pro to Leu mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Pro349Leu	c.1046C>T	6	349	EXO1 stabilization		Small rearrangement	Ts	C->T	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 246 5_2001168_20001550_AAA955 - 5 2844 5_200116820001550AAA955 - 5
p.Pro415Leu	c.1244C>T	7	415	EXO1 stabilization		Small rearrangement	Ts	C->T	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 900 20_20-2284_2284-01_--- - 20
p.Pro622Leu	c.1865C>T	12	622	ATPase		Small rearrangement	Ts	C->T	3
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3110 37_L14.23529969167426 - 37 3111 37_L14.23527879167425 - 37 3112 37_L14.23529971167427 - 37
p.Pro670Leu	c.2009C>T	13	670	ATP binding		Small rearrangement	Ts	C->T	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 65 2_02-NJ21_718_718 - 2 910 20_20-2819_2819-02_12049 - 20
p.Pro696Leu	c.2087C>T	13	696	ATPase		Small rearrangement	Ts	C->T	3
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3227 19_2762327623-00127623-001 - 19 911 20_20-3124_3124-01_12479 - 20 2330 SO_-1001---G00329 - 71