The UMD-MSH2 mutations database
Leu to Val mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Leu92Val	c.274C>G	2	92	Mismatch binding		Small rearrangement	Tv	C->G	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3039 25_HCC-3385141046AML36 - 25
p.Leu128Val	c.382C>G	3	128	Connector		Small rearrangement	Tv	C->G	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 1028 31_H230_H230_1_H230_1_A - 31
p.Leu279Val	c.835C>G	5	279	EXO1 stabilization		Small rearrangement	Tv	C->G	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3048 19_2425324253-00124253-001 - 19
p.Leu341Val	c.1021C>G	6	341	EXO1 stabilization		Small rearrangement	Tv	C->G	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 392 8_35618_28061977_08-87130 - 8
p.Leu387Val	c.1159C>G	7	387	EXO1 stabilization		Small rearrangement	Tv	C->G	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 12 2_02-DDM3140_19624_19624 - 2 260 5_2007265_20073037_AAB908 - 5