The UMD-MSH2 mutations database
Leu to Pro mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Leu173Pro	c.518T>C	3	173	Connector		Small rearrangement	Ts	T->C	4
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3171 17_122062318198001--- - 17 455 8_34437_B051630_05-1310 - 8 456 8_34437_B052702_ARN G1 - - 8 457 8_34876_11081924_B051630 - 8
p.Leu330Pro	c.989T>C	6	330	EXO1 stabilization		Small rearrangement	Ts	T->C	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 2398 SO_-1308---G01571 - 71
p.Leu341Pro	c.1022T>C	6	341	EXO1 stabilization		Small rearrangement	Ts	T->C	92
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 147 4_6146_19441_1709 - 4 148 4_6146_19441_--- - 4 393 8_F900_17041974_08-019080 - 8 394 8_F900_27051962_08-755080 - 8 395 8_F900_16071933_B032699 - 8 396 8_F900_20061946_B032770 - 8 397 8_F900_7111939_B032772 - 8 398 8_F900_B032701_G2-NÁ145 - 8 608 19_12548_12548-001_12548- - 19 946 31_H1299_H1299-2_H1299-2A - 31 947 31_H62_H62_1_H62_1_A - 31 1113 37_L97.02_254_186 - 37 1114 37_L97.02_261_189 - 37 1115 37_L98.05_264_198 - 37 1116 37_L97.02_604_604 - 37 1117 37_L01.03_885_3000 - 37 1118 37_L01.03_1076_5913 - 37 1119 37_L01.03_1223_7980 - 37 1120 37_L97.02_1528_12943 - 37 1121 37_L03.14_1635_14364 - 37 1122 37_L03.17_1656_14767 - 37 1123 37_L03.28_1826_17115 - 37 1124 37_L03.32_1895_18473 - 37 1125 37_L03.32_1539_18474 - 37 1126 37_L03.17_2607_28443 - 37 1127 37_L03.32_3704_39373 - 37 1128 37_L03.32_3705_39374 - 37 1129 37_L03.17_3776_39789 - 37 1130 37_L03.17_3775_39791 - 37 1131 37_L04.15_4181_43889 - 37 1132 37_L04.31_4255_44404 - 37 1133 37_L04.32_4545_46932 - 37 1134 37_L06.35_5323_52588 - 37 1135 37_L03.28_5611_54626 - 37 1136 37_L03.28_5612_54628 - 37 1137 37_F07.042_5983_56657 - 37 1138 37_L06.35_6169_58578 - 37 1139 37_L04.32_6220_59388 - 37 1140 37_F07.042_5484_60936 - 37 1141 37_F07.042_6742_64108 - 37 1142 37_F07.042_6903_65405 - 37 1143 37_F07.042_6982_66251 - 37 1144 37_F07.042_6983_66252 - 37 1145 37_F07.042_6984_66296 - 37 1146 37_F07.042_6985_66297 - 37 1147 37_F07.042_7042_66742 - 37 1148 37_F07.042_7044_66760 - 37 1149 37_L03.07_10421_87888 - 37 1150 37_L03.07_10521_88380 - 37 1151 37_L10.025_9233_94464 - 37 1152 37_L03.32_12212_97178 - 37 1153 37_L10.025_13041_100707 - 37 1154 37_L10.068_10204_102040 - 37 1155 37_L06.62_16434_121804 - 37 1156 37_L11.079_17264_128245 - 37 1157 37_L06.62_20384_131797 - 37 1158 37_L06.62_20385_131798 - 37 1159 37_L06.62_20384_131844 - 37 1160 37_L06.62_20385_131845 - 37 1161 37_L04.15_2295_23769/2973 - 37 1162 37_L04.32_2485_27070/3127 - 37 1163 37_L06.06_3822_40302/4030 - 37 1164 37_L06.09_3868_40766/4076 - 37 1165 37_L06.35_4246_44401/4440 - 37 1166 37_L03.07_1754_--- - 37 1512 7_2606538E02381 - 7 1534 7_26061443E03147 - 7 1557 7_26061428E03286 - 7 2067 7_26064804E051547 - 7 2333 SO_-1309---G00337 - 71 2343 SO_-1309---G00781 - 71 2344 SO_-1309---G00785 - 71 2350 SO_-2110---G00816 - 71 2433 SO_-2705---G02445 - 71 2514 SO_-2705---G05074 - 71 2550 SO_2606---G05759 - 71 2841 37_L03.3222244138953 - 37 2842 37_L06.6221916137796 - 37 2843 37_L07.4223084142382 - 37 2923 41_HNPCC467HNPCC467001 - 41 2924 19_L11.07917264118451 - 19 2925 19_L03.01718072122163 - 19 2926 19_L06.62424348172 - 19 2927 19_L06.6218507124297 - 19 2928 19_L06.6218326123325 - 19 2929 19_L06.6218329123326 - 19 2930 19_L06.6216434121804 - 19 2931 19_L10.06810204107108 - 19 2932 31_H1299H1299-1H1299-1A - 31 3076 37_L03.0729365165192 - 37 3077 37_L04.3226377155302 - 37 3078 37_L13.10826643156363 - 37
p.Leu602Pro	c.1805T>C	12	602	Lever		Small rearrangement	Ts	T->C	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 736 19_3154_3154-001_3154-001 - 19 737 19_3154_3154-002_3154-002 - 19