The UMD-MSH2 mutations database
Ile to Deletion mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Ile192GlufsX10	c.574_610del	3	192	Connector		Small rearrangement	Fr.	Stop at 201	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 383 6_604004_198004722_S0571 - 6 2758 SO_-5581---G08693 - 71
p.Tyr238ArgfsX7	c.711_714delTTAT	4	237	Connector		Small rearrangement	Fr.	Stop at 244	7
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3243 8_419359579808-700241 - 8 462 8_41935_13071964_08-30000 - 8 463 8_41935_61153_08-952090EG - 8 464 8_41935_85516_08-994031EG - 8 3044 8_419359072208-341331EGS - 8 3045 8_419359072108-241331EGS - 8 3242 8_419359408808-450241 - 8
p.Ile685MetfsX25	c.2055delA	13	685	ATP binding		Small rearrangement	Fr.	Stop at 709	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 760 19_8759_8759-001_8759-001 - 19 761 19_8759_8759-007_8759-007 - 19
p.Ile745X	c.2233_2243del	14	745	ATPase		Small rearrangement	Fr.	Stop at 745	3
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 769 19_14104_14104-001_14104- - 19 1750 7_-5801---E041035 - 7 2119 7_-58012957E060150 - 7
p.Ile746del	c.2235_2237delAAT	14	745	ATPase		Small rearrangement	InF	In frame del	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 1400 41_HNPCC019_HNPCC019002_- - 41
p.Ile747MetfsX16	c.2241delA	14	747	ATPase		Small rearrangement	Fr.	Stop at 762	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 770 19_2938_2938-001_2938-001 - 19
p.Ile841X	c.2521delA	15	841	ATPase		Small rearrangement	Fr.	Stop at 841	4
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 87 2_02-SG417-Cochin_2046_20 - 2 1017 31_H224_H224_1_H224_1_A - 31 1018 31_H224_H224-2_H224-2A - 31 1019 31_H224_H224-2_H224-2B - 31
p.Ile883_Gln885delinsMet	c.2649_2654del	16	883	MSH3/MSH6 interaction		Small rearrangement	InF	In frame del	5
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 96 2_02-ACT2836_18901_18901 - 2 97 2_02-ACT2836_18901_18901 - 2 3035 2_02-ACT283639226214118445 - 2 3036 2_02-ACT283639858214175421 - 2 3037 2_02-ACT283639859214175423 - 2