The UMD-MSH2 mutations database
Gly to Asp mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Gly25Asp	c.74G>A	1	25	Mismatch binding		Small rearrangement	Ts	G->A	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 2245 7_1150012096E100573 - 7
p.Gly322Asp	c.965G>A	6	322	Lever		Small rearrangement	Ts	G->A	46
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3197 37_L14.112-E27789160133 - 37 134 2_02-ACT1732_13833_13833 - 2 345 5_2003205_P0024099_AAA322 - 5 346 5_2004214_20042277_AAA342 - 5 347 5_2005126_P0028209_AAA743 - 5 348 5_2008178_20081746_AAC468 - 5 349 5_2008335_20083639_AAC712 - 5 350 5_2008412_20080544_AAC855 - 5 351 5_2009263_20092863_AAD397 - 5 352 5_2009490_20082277_AAD773 - 5 353 5_2004214_20105731_AAE705 - 5 354 5_2010625_P0045640_AAE780 - 5 487 14_F1234_06C497_06C497 - 14 925 20_20-1945_1945-02_6867 - 20 926 20_20-3135_3135-01_12512 - 20 927 20_20-1273_1273-01_--- - 20 1056 31_H122_H122_1_H122_1_A - 31 1057 31_H122_H122_2_H122_2_A - 31 1058 31_H125_H125_1_H125_1_A - 31 1059 31_H76_H76_1_H76_1_A - 31 1060 31_H77_H77_1_H77_1_A - 31 1481 7_2637644E02055 - 7 1528 7_26371441E03122 - 7 1540 7_2637644E03220 - 7 1548 7_23981581E03272 - 7 1552 7_23981582E03273 - 7 1553 7_23981582E03273 - 7 1554 7_26371441E03274 - 7 1562 7_2398270E03317 - 7 1773 7_46132846E041196 - 7 1859 7_23913699E050358 - 7 1860 7_18123697E050359 - 7 2083 7_49264909E060036 - 7 2136 7_-6186---E060221 - 7 2140 7_-61865037E060221 - 7 2271 7_216456E2K083 - 7 2274 7_2391226E2K184 - 7 2281 7_1812262E2K241 - 7 2296 7_2398270E2K249 - 7 2553 SO_-3987---G05789 - 71 2646 SO_-4822---G07233 - 71 2709 SO_-5290---G08086 - 71 2757 SO_-55623187G08631 - 71 2882 37_L12.09920479132145/132146 - 37 2978 5_200938320101032AAF427 - 5 3196 37_L14.00425846153593 - 37
p.Gly548Asp	c.1643G>A	10	548	EXO1 stabilization		Small rearrangement	Ts	G->A	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 41 2_02-ACT1727_13913_13913 - 2
p.Gly674Asp	c.2021G>A	13	674	ATP binding		Small rearrangement	Ts	G->A	4
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 496 17_Paris - F00149_5001157 - 17 1411 SO_-650---5508 - 71 2382 SO_-650---G01495 - 71 2860 5_201163420115747AAF838 - 5