The UMD-MSH2 mutations database
Glu to Lys mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Glu278Lys	c.832G>A	5	278	EXO1 stabilization		Small rearrangement	Ts	G->A	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 127 2_02-DDM3432_20457_20457 - 2
p.Glu530Lys	c.1588G>A	10	530	EXO1 stabilization		Small rearrangement	Ts	G->A	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 2639 SO_-4757---G07125 - 71
p.Glu561Lys	c.1681G>A	11	561	EXO1 stabilization		Small rearrangement	Ts	G->A	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 50 2_02-ACT1727_13913_13913 - 2 180 4_98H02_---_385 - 4
p.Glu749Lys	c.2245G>A	14	749	ATPase		Small rearrangement	Ts	G->A	30
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 206 4_112_---_--- - 4 771 19_6767_6767-001_6767-001 - 19 772 19_6767_6767-002_6767-002 - 19 773 19_7677_7677-003_7677-003 - 19 774 19_7677_7677-006_7677-006 - 19 1012 31_H185_H185-1_H185-1A - 31 1276 37_L08.026-E_6657_63435 - 37 1277 37_L08.082_7724_71663 - 37 1401 41_HNPCC014_HNPCC014001_- - 41 1402 41_HNPCC014_HNPCC014002_- - 41 1410 SO_-945---5232 - 71 2068 7_-6146---E051561 - 7 2069 7_-61464820E051561 - 7 2329 SO_-945---G00325 - 71 2342 SO_-945---G00765 - 71 2346 SO_-945---G00794 - 71 2348 SO_-945---G00801 - 71 2566 SO_-4060---G06027 - 71 2706 SO_-5207---G07953 - 71 2957 19_L10.070-E13475102146 - 19 3028 19_2519525195-00125195-001 - 19 3128 19_76777677-0097677-009 - 19 3129 19_76777677-0107677-010 - 19 3130 19_76777677-0117677-011 - 19 3131 19_2145121451-00121451-001 - 19 3132 19_2519525195-00425195-004 - 19 3133 19_2702627026-00127026-001 - 19 3134 19_76777677-0127677-012 - 19 3135 19_2519525195-00725195-007 - 19 3136 37_L12.135-E27902160527 - 37
p.Glu809Lys	c.2425G>A	14	809	ATPase		Small rearrangement	Ts	G->A	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3138 17_130457716416001--- - 17
p.Glu886Lys	c.2656G>A	16	886	MSH3/MSH6 interaction		Small rearrangement	Ts	G->A	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 2873 2_02-DDM978032693212226442 - 2