The UMD-MSH2 mutations database
Glu to Deletion mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Glu7GlyfsX57	c.20delA	1	7	Mismatch binding		Small rearrangement	Fr.	Stop at 63	2
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 70 2_02-DDM2931_19124_19124 - 2 1075 33_TNN193__03-099 - 33
p.Glu28ArgfsX36	c.82delG	1	28	Mismatch binding		Small rearrangement	Fr.	Stop at 63	3
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 340 5_2007360_20080819_AAC350 - 5 2428 SO_-2638---G02259 - 71 2506 SO_-2638---G04940 - 71
p.Glu56ArgfsX8	c.166delG	1	56	Mismatch binding		Small rearrangement	Fr.	Stop at 63	4
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 179 4_T04150_18205_1227 - 4 362 6_604150_200404598_S7027 - 6 714 19_11336_11336-001_11336- - 19 987 31_H203_H203-2_H203-2A - 31
p.Glu290_Gln324del	c.868_972del	5	290	EXO1 stabilization		Small rearrangement	InF	In frame del	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 2467 SO_-3104---G03265 - 71
p.Glu290AspfsX2	c.870delA	5	290	EXO1 stabilization		Small rearrangement	Fr.	Stop at 291	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 2224 7_89859230E081109 - 7
p.Glu529LysfsX14	c.1585delG	10	529	EXO1 stabilization		Small rearrangement	Fr.	Stop at 542	10
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 420 8_43170_13021957_08-02501 - 8 421 8_43170_81585_08-813221EG - 8 1212 37_L07.001_11145_91813 - 37 1213 37_L12.042_16966_134173 - 37 1214 37_L12.042_16966_127614/1 - 37 1215 37_F07.001_5133_--- - 37 1888 7_-5421---E050558 - 7 1889 7_-54214014E050558 - 7 2739 SO_-5421---G08387 - 71 3095 37_L13.10330816170276 - 37
p.Glu569IlefsX2	c.1705_1706delGA	11	569	EXO1 stabilization		Small rearrangement	Fr.	Stop at 570	12
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 1068 33_TNN 149__02-817 - 33 1377 41_HNPCC052_HNPCC052001_- - 41 1378 41_HNPCC052_HNPCC052003_- - 41 1379 41_HNPCC052_HNPCC052004_- - 41 1380 41_HNPCC052_HNPCC052005_- - 41 1381 41_HNPCC052_HNPCC052008_- - 41 2399 SO_-2389---G01667 - 71 2578 SO_-4192---G06229 - 71 3055 31_H1746H1746-1H1746-1A - 31 3102 19_1941319413-01519413-015 - 19 3103 19_1941319413-01619413-016 - 19 3206 2_02-PKO1372343357215114430 - 2
p.Ala573ProfsX17	c.1716delA	11	572	EXO1 stabilization		Small rearrangement	Fr.	Stop at 589	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 717 19_15422_15422-001_15422- - 19
p.Glu731LysfsX14	c.2191delG	13	731	ATPase		Small rearrangement	Fr.	Stop at 744	8
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 1360 38_18_A1_633 - 38 1361 38_18_A2_1574 - 38 1362 38_18_A3_1576 - 38 1363 38_18_A4_1882 - 38 2477 SO_-3204---G03430 - 71 2523 SO_-3204---G05177 - 71 2563 SO_-3204---G05986 - 71 3027 19_2438224382-00124382-001 - 19
p.Glu853GlyfsX39	c.2558delA	15	853	ATPase		Small rearrangement	Fr.	Stop at 891	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 2376 SO_-403---G01450 - 71
p.Glu859_Gln861del	c.2576_2584del	15	859	Helix-turn-helix		Small rearrangement	InF	In frame del	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 320 5_2007070_20070899_AAB618 - 5
p.Glu878AlafsX3	c.2633_2634delAG	15	878	MSH3/MSH6 interaction		Small rearrangement	Fr.	Stop at 880	7
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3236 19_2807228072-00228072-002 - 19 321 5_2004041_P0024840_AAA113 - 5 322 5_2004041_20050741_AAA622 - 5 323 5_2004041_20013672_AAA882 - 5 324 5_2004041_20062113_AAB216 - 5 325 5_2004041_20062114_AAB222 - 5 3235 19_2807228072-00128072-001 - 19
p.Glu881LysfsX11	c.2641delG	16	881	MSH3/MSH6 interaction		Small rearrangement	Fr.	Stop at 891	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 1022 31_H498_H498-1_H498-1A - 31