The UMD-MLH1 mutations database
Mutation c.IVS1+36T>A (c.116+36T>A)

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MLH1	MSH2	MSH6	MUTYH	APC
19_2740927409-00127409-001	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Index case (27409-001) : endometrium cancer at the age of 68. Father : colorectal cancer at the age of 54. Paternal aunt : ovary cancer	24/09/15	19 (Rouen)	---
MMR function in tumor cells	MSI / MLH1+MSH2+MSH6- (27409-001)	24/09/15	19 (Rouen)	---

Biological significance	Date	Comment
UV	25/09/15	---