The UMD-MLH1 mutations database
Mutation c.264dup

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MLH1	MSH2	MSH6	MUTYH	APC
19_2845428454-00128454-001	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
MMR function in tumor cells	MSS / MLH1+MSH2+MSH6+PMS2? (28454-001)	24/09/15	19 (Rouen)	---
Clinical phenotype	Index case (28454-001) : adenoma with high-grade dysplasia at the age of 20. Maternal grandmother : colorectal cancer at the age of 61	24/09/15	19 (Rouen)	---

Biological significance	Date	Comment
Causal	24/09/15	---