The UMD-MLH1 mutations database
Mutation c.1228delG

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MLH1	MSH2	MSH6	MUTYH	APC
19_2765827658-00127658-001	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
MMR function in tumor cells	MSI	24/09/15	19 (Rouen)	---
Clinical phenotype	Amsterdam +. Index case (27658-001) : 2 colon cancers at the ages of 42 and 51	24/09/15	19 (Rouen)	---

Biological significance	Date	Comment
Causal	25/09/15	---