The UMD-MLH1 mutations database
Record ID: 385

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.1410_1558delp.Arg470SerfsX8

wt codonwt aamutant codonmutant aamutational eventmutation type
AGAArgdel149cFs.Stop at 477Fr.

StructureKey Residue (HCD)Pyrimidin doubletCpG
NLS 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Patient and sample data


Sample IDPatient status
8_F45_46313_08-701011BARelative

Clinical data


Symptom

Reference


Reference IDReference
8Unpublished data