The UMD-MEN1 database has been set up in a joined national effort through the network of 4 diagnostic laboratories to provide up-to-date information about mutations of the MEN1 gene, identified in patients presented with Multiple Endocrine Neoplasia type 1 (MEN1) syndrom. The main roles of TENGEN (Oncogenetic Network on NeuroEndocrine Tumors) are to establish specific care, to liven up meetings of multidisciplinary dialogs, and to develop clinical research.
This database of MEN1 mutations was developed using the Universal mutation Database tool.
||Institut de Biochimie et Biologie Moléculaire, CHRU Lille
||Service de Biochimie et Génétique Moléculaires, Hôpital Cochin, APHP
||Département de génétique, Groupement Hospitalier Est, Hospices Civils de Lyon (HCL), Lyon
||Laboratoire de Biochimie, Bâtiment IFB, Hôpital Purpan, CHU Toulouse
||Laboratoire de biologie moléculaire, Hôpital La Conception, APHM
Data from genetics laboratories are sent to Marseille for inclusion and curation into the database. Data from the curation center are updated by the Bioinformatics team of MMG, INSERM UMR_1251 into the UMD-MEN1 French database.
This work is supported by grant from Institut National du CAncer (INCA)
For further details about TENGEN, refer to website
If you want to submit a variation, please contact Pauline Romanet or Amira Mohamed.
For technical problem or difficulty in using the database, please contact Amira Mohamed.
The UMD-MEN1 Locus Specific Databases constitute the intellectual property of the inventors of the database. Any unauthorized copying, storage or distribution of this material without written permission from the inventors would lead to copyright infringement with possible ensuing litigation.
For further details, please refer to Directive 96/9/EC of the European Parliament and of the Council of 11 March 1996 on the legal protection of databases.