The UMD-MEN1 mutations database
Nucleotides modifications

This function takes into account only small rearrangements.

For each of the four bases are displayed its number in the MEN1 cDNA at each codon's position as well as the corresponding mutability. For each base are also displayed the various substitutions and small deletions and insertions.

from A from C from G from T
Position in codon
1st
2nd
3rd
1st
2nd
3rd
1st
2nd
3rd
1st
2nd
3rd
Number in sequence
120
182
60
184
151
250
222
121
225
85
157
76
Mutability
360
546
52
552
453
213
666
340
256
255
430
76
to A
.
.
.
5
36
21
62
30
39
2
1
.
to C
11
.
.
.
.
.
22
15
12
7
36
1
to G
5
34
2
4
13
11
.
.
.
.
14
7
to T
7
4
7
243
25
32
30
20
7
.
.
.
Deletion
146
48
22
92
2
13
29
7
56
5
35
11
Insertion
19
16
2
20
3
32
12
118
14
1
5
13

Mutability: for each base, the significance of a mutation is defined by the ability to produce a new Amino Acid. In these conditions, the position of the specific base in the codon has a major incidence. If any substitution result in a new Amino Acid, its individual mutability is 3. If only two substitutions result in a new Amino Acid, its mutability is 2... The Mutability at a specific position in the codon (first base=1st, second base=2nd and third base=3rd) is defined by the addition of all individual mutability for this base in each codon of the coding sequence.