The UMD-MEN1 mutations database
Record ID: 919

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.1341T>Gp.Phe447LeuHeterozygousLIKELY CAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
TTTPheTTGLeuT->GTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Pem,NM,RP,HD,CH Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 47 (Polymorphism)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-BL01-S25L-ProbandFemale54

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
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