The UMD-MEN1 mutations database
Record ID: 915

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.1273G>Ap.Glu425LysHeterozygousUV

wt codonwt aamutant codonmutant aamutational eventmutation type
GAGGluAAGLysG->ATs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju,Pem,NM,RP,HD,CH Yes, non coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 41 (Polymorphism)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-PE18-R15G-ProbandMale

Phenotypic groupDisease
Not availablePlease contact curator

Reference


Reference IDPubMed IDReference
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