The UMD-MEN1 mutations database
Record ID: 806

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.1080C>Tp.Ile360IleHeterozygousLIKELY NEUTRAL

wt codonwt aamutant codonmutant aamutational eventmutation type
ATCIleATTIleC->TTs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju,NF,Pem,NM,RP,FA,HD Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): Bgl II, Dpn I, Dpn II, Mbo I, Sau3A I

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 23 (Polymorphism)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-TR01-C01T-ProbandFemale49

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
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