The UMD-MEN1 mutations database
Record ID: 595

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.781C>Tp.Gln261XHeterozygousCAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
CAGGlnTAGStopC->TTs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Sm,NM,NMH,FA,HD NoNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): BspW I

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-WA12-S25L-ProbandFemale28

Phenotypic groupDisease
ModeratePlease contact curator

Reference


Reference IDPubMed IDReference
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