The UMD-MEN1 mutations database
Record ID: 543

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.IVS3-22Del12 (c.655-22Del12)HeterozygousMutation

wt codonwt aamutant codonmutant aamutational eventmutation type
AGCSerspl-22Spl.Del12Tv

StructureKey Residue (HCD)Pyrimidin doubletCpG
 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Impact on splicing
Splice site type Wild type sequence CV Mutant type sequence CV Variation (%)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-RO14-A14N-RelativeFemale77

Phenotypic groupDisease
asymptomaticPlease contact curator

Reference


Reference IDPubMed IDReference
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