The UMD-MEN1 mutations database
Record ID: 520

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.533C>Tp.Ser178PheHeterozygousUV

wt codonwt aamutant codonmutant aamutational eventmutation type
TCTSerTTTPheC->TTs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju,Sm,NMH,HD,NM Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 76 (Pathogenous)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-OU22-E20I-ProbandMale13

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
0Í