The UMD-MEN1 mutations database
Record ID: 451

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.467G>Tp.Gly156ValHeterozygousLIKELY CAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
GGTGlyGTTValG->TTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju,Sm,NMH,HD,NM Yes, non coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): Hpa II, Msp I

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 76 (Pathogenous)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-GA09-I19A-ProbandMale46

Phenotypic groupDisease
ModeratePlease contact curator

Reference


Reference IDPubMed IDReference
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