The UMD-MEN1 mutations database
Record ID: 427

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.125G>Tp.Gly42ValHeterozygousLIKELY CAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
GGCGlyGTCValG->TTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Sm, NM Yes, non coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 71 (Probably pathogenous)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-AV09-S05V-ProbandFemale

Phenotypic groupDisease
Not availablePlease contact curator

Reference


Reference IDPubMed IDReference
0Í