The UMD-MEN1 mutations database
Record ID: 393

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.38T>Gp.Leu13ArgHeterozygousLIKELY CAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
CTGLeuCGGArgT->GTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju, NM, RP Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): BstU I, Dsa I, Hae II, Sac II
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 76 (Pathogenous)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-CO18-M01R-ProbandMale50

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
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