The UMD-MEN1 mutations database
Record ID: 322

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.202_206dupp.Asp70ProfsX51HeterozygousCAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
CCCProins5cFs.Stop at 120Fr.

StructureKey Residue (HCD)Pyrimidin doubletCpG
Sm, NM 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-PO20-E18I-ProbandMale38

Phenotypic groupDisease
ModeratePlease contact curator

Reference


Reference IDPubMed IDReference
510664520
Morelli, A., Falchetti, A., Martineti, V., Becherini, L., Mark, M., Friedman, E., & Brandi, M. L. (2000). MEN1 gene mutation analysis in Italian patients with multiple endocrine neoplasia type 1. European Journal of Endocrinology / European Federation of Endocrine Societies, 142(2), 131?7. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/10664520