The UMD-MEN1 mutations database
Record ID: 299

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.69delTp.Phe23LeufsX96HeterozygousCAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
TTTPhedel1cFs.Stop at 118Fr.

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju, NM, RP 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-ME09-S15N-ProbandFemale52

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
912112656
Wautot, V., Vercherat, C., Lespinasse, J., Chambe, B., Lenoir, G. M., Zhang, C. X., ? Calender, A. (2002). Germline mutation profile of MEN1 in multiple endocrine neoplasia type 1: search for correlation between phenotype and the functional domains of the MEN1 protein. Human Mutation, 20(1), 35?47. doi:10.1002/humu.10092