The UMD-MEN1 mutations database
Record ID: 217

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.IVS10+39T>G (c.1833+39T>G)p.X611Spl.ext175HeterozygousUV

wt codonwt aamutant codonmutant aamutational eventmutation type
TGAStopspl+39Spl.T->GTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Impact on splicing
Splice site type Wild type sequence CV Mutant type sequence CV Variation (%)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
04-LA14-C08R-ProbandMale42

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
0Í