The UMD-MEN1 mutations database
Record ID: 1980

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.IVS4-15Del2 (c.784-15Del2)LIKELY NEUTRAL

wt codonwt aamutant codonmutant aamutational eventmutation type
AAGLysspl-15Spl.Del2Tv

StructureKey Residue (HCD)Pyrimidin doubletCpG
 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Impact on splicing
Splice site type Wild type sequence CV Mutant type sequence CV Variation (%)
Cryptic Acceptor?
tcggctcctagAAGC
19 _
ggctcctagAAGCT
74.1 _ *
74.4 %

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
01-DU10-A04-ProbandFemale30

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
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