The UMD-MEN1 mutations database
Record ID: 1958

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.658T>Cp.Trp220ArgLIKELY CAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
TGGTrpCGGArgT->CTs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju,Sm,NM,NMH,FA,HD Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): Cfr10 I, Hpa II, Msp I, Nae I
Lost restriction site(s): Alu I

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 76 (Pathogenous)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-BO21-S01-ProbandFemale

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
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