The UMD-MEN1 mutations database
Record ID: 1890

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.1724T>Gp.Ile575SerHeterozygousLIKELY CAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
ATCIleAGCSerT->GTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Sm,ASK,CH Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 76 (Pathogenous)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
04-EQ21-C08R-ProbandFemale57

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
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