The UMD-MEN1 mutations database
Record ID: 1877

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.609delCp.Asn203LysfsX21HeterozygousCAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
AACAsndel1cFs.Stop at 223Fr.

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju,Sm,NMH,HD,NM 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
04-CA22-C15R-RelativeFemale43

Phenotypic groupDisease
ModeratePlease contact curator

Reference


Reference IDPubMed IDReference
1316563611
J*ger, A. C., Friis-Hansen, L., Hansen, T. V. O., Eskildsen, P. C., S¿lling, K., Knigge, U., ? Nielsen, F. C. (2006). Characteristics of the Danish families with multiple endocrine neoplasia type 1. Molecular and Cellular Endocrinology, 249(1-2), 123?32. doi:10.1016/j.mce.2006.02.008