The UMD-MEN1 mutations database
Record ID: 1860

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.1395C>Tp.Ala465AlaHeterozygousLIKELY NEUTRAL

wt codonwt aamutant codonmutant aamutational eventmutation type
GCCAlaGCTAlaC->TTs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Pem,NM,CH Yes, coding strandYes

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): Dde I
Lost restriction site(s): Eag I, Hae III, Sfi I

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 18 (Polymorphism)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
04-NI03-F01B-RelativeMale34

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
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