The UMD-MEN1 mutations database
Record ID: 1812

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.1382_1389delp.Glu461GlyfsX67HeterozygousCAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
GAGGludel8bFs.Stop at 527Fr.

StructureKey Residue (HCD)Pyrimidin doubletCpG
Pem,NM,CH Yes, coding strand

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): Csp6 I, Rsa I, Sca I
Lost restriction site(s): Dde I

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
02-HO18-M15N-ProbandFemale69

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
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