The UMD-MEN1 mutations database
Record ID: 1669

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.134A>Gp.Glu45GlyHeterozygousCAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
GAGGluGGGGlyA->GTs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Sm, NM Yes, non coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 76 (Pathogenous)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
02-DE13-K01D-ProbandFemale27

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
3711216636
Large and asymptomatic pancreatic islet cell tumor in a patient with multiple endocrine neoplasia type 1 Makoto Sato , Minoru Kihara, Akiko Nishitani, Koji Murao, Shoji Kobayashi, Akira Miyauchi, Jiro Takahara