The UMD-MEN1 mutations database
Record ID: 1598

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.IVS9-1G>T (c.1351-1G>T)HeterozygousCAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
GTGValspl-1Spl.G->TTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Pem,NM,CH 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Impact on splicing
Splice site type Wild type sequence CV Mutant type sequence CV Variation (%)
Acceptor
ccactggcccagGT
84.9 _
ccactggcccatGT
56 _ *
-34.1 %

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
02-GO21-R01J-ProbandMale35

Phenotypic groupDisease
Not availablePlease contact curator

Reference


Reference IDPubMed IDReference
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