The UMD-MEN1 mutations database
Record ID: 1564

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.415C>Ap.His139AsnHeterozygousLIKELY CAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
CACHisAACAsnC->ATv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju, Sm, NM Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): Apa I, Bsp120 I

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 47 (Polymorphism)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
02-PE19-D15M-ProbandFemale50

Phenotypic groupDisease
ModeratePlease contact curator

Reference


Reference IDPubMed IDReference
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