The UMD-MEN1 mutations database
Record ID: 1549

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.1066G>Tp.Glu356XHeterozygousCAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
GAAGluTAAStopG->TTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju,NF,Pem,NM,RP,FA,HD Yes, non coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): Cfr10 I
Lost restriction site(s): BstK I, Dsa V, ScrF I

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
02-LE16-R01Y-RelativeMale13

Phenotypic groupDisease
asymptomaticPlease contact curator

Reference


Reference IDPubMed IDReference
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