The UMD-MEN1 mutations database
Record ID: 1521

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.IVS9-24A>G (c.1351-24A>G)HeterozygousUV

wt codonwt aamutant codonmutant aamutational eventmutation type
GTGValspl-24Spl.A->GTs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Pem,NM,CH 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Impact on splicing
Splice site type Wild type sequence CV Mutant type sequence CV Variation (%)
Branch Point
ctctcac
99.9 _
ctctcGc
70.1 _ *
-29.9 %

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
02-BE01-V09R-ProbandFemale28

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
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