The UMD-MEN1 mutations database
Record ID: 1324

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.794G>Ap.Trp265XHeterozygousCAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
TGGTrpTAGStopG->ATs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Sm,NM,NMH,FA,HD Yes, non coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): Alu I, Rma I
Lost restriction site(s): none

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
01-BU18-D15M-ProbandFemale57

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
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