The UMD-MEN1 mutations database
Record ID: 125

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.1034C>Ap.Ala345AspHeterozygousUV

wt codonwt aamutant codonmutant aamutational eventmutation type
GCCAlaGACAspC->ATv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju,NF,Pem,NM,RP,FA,HD Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): Hae III

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 82 (Pathogenous)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
04-CA14-D01N-ProbandMale49

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
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