The UMD-MEN1 mutations database
Record ID: 1225

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.1382_1390dupp.Glu461delinsGluAlaGluGluHeterozygousCAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
GAGGluins9bInFIn frame insFr.

StructureKey Residue (HCD)Pyrimidin doubletCpG
Pem,NM,CH Yes, non coding strand

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): BsiY I
Lost restriction site(s): BsiE I, BsiY I, BspW I, BspW I, Eae I, Eag I, Hae III, Hae III, Mcr I, Sfi I

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
03-RO19-B05R-RelativeMale55

Phenotypic groupDisease
asymptomaticPlease contact curator

Reference


Reference IDPubMed IDReference
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