The UMD-MEN1 mutations database
Trp to Stop mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Trp126X	c.378G>A	2	126	Sm, NM		Small rearrangement	Ts	G->A	4
UMD_id Sample ID Gender Mutation status Variation class Family ID References 1457 01-VA14-C05D-979 Male Heterozygous CAUSAL 15 1358 01-DE19-P01T-953 Male Heterozygous CAUSAL W153 31 1359 03-DE19-S15P-989 Female Heterozygous CAUSAL W153 31 1360 03-DE19-C01R-991 Female Heterozygous CAUSAL W153 31
p.Trp265X	c.794G>A	5	265	Sm,NM,NMH,FA,HD		Small rearrangement	Ts	G->A	2
UMD_id Sample ID Gender Mutation status Variation class Family ID References 1323 01-BU09-S20E-975 Female Heterozygous CAUSAL W1066 0 1324 01-BU18-D15M-950 Female Heterozygous CAUSAL W1066 0
p.Trp265X	c.795G>A	5	265	Sm,NM,NMH,FA,HD		Small rearrangement	Ts	G->A	6
UMD_id Sample ID Gender Mutation status Variation class Family ID References 666 03-LA16-S20E-968 Male Heterozygous CAUSAL W1015 12 667 03-LA16-J01M-939 Male Heterozygous CAUSAL W1015 12 670 03-BO21-M01R-956 Female Heterozygous CAUSAL W79 12 671 03-GU09-D15M-961 Male Heterozygous CAUSAL W79 24 672 03-GU09-P01U-932 Male Heterozygous CAUSAL W79 12 681 03-LA16-L01U-001 Female Heterozygous CAUSAL W1015 12
p.Trp436X	c.1308G>A	9	436	Pem,NM,RP,HD,CH		Small rearrangement	Ts	G->A	12
UMD_id Sample ID Gender Mutation status Variation class Family ID References 160 03-GE18-V09R-985 Female Heterozygous CAUSAL W134 14 161 04-TI05-L01U-988 Female Heterozygous CAUSAL w2075 14 825 03-CA18-M09C-956 Male Heterozygous CAUSAL W253 23 839 03-TA22-F18E-970 Male Heterozygous CAUSAL W76 23 840 03-TA22-O12I-970 Male Heterozygous CAUSAL W76 23 901 03-CA18-H21G-934 Female Heterozygous CAUSAL W253 15 910 03-SO21-A14N-967 Female Heterozygous CAUSAL W2075 14 911 03-SO21-F12O-993 Female Heterozygous CAUSAL W2075 14 921 03-CA12-C25R-987 Male Heterozygous CAUSAL W253 14 1121 03-GE18-S25L-974 Female Heterozygous CAUSAL W134 14 1122 03-GE18-M01R-954 Female Heterozygous CAUSAL W134 14 1123 03-GE18-A12I-980 Female Heterozygous CAUSAL W134 14
p.Trp471X	c.1413G>A	10	471	Pem,NM,CH		Small rearrangement	Ts	G->A	1
UMD_id Sample ID Gender Mutation status Variation class Family ID References 1213 03-RO21-L01U-965 Female Heterozygous CAUSAL 32